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HGF regulation of RPE proliferation in an IL-1beta/retinal hole-induced rabbit model of PVR.

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Citations

0

References

2002

Year

Gregory I. Liou, Vytautas A. Pakalnis, Suraporn Matragoon, Sara Samuel, M. Ali Behzadian, Justin N. Baker, Ibrahim E. Khalil, Penny Roon, Ruth B. Caldwell, Richard C. Hunt,
PubMed

Abstract

These data suggest that the presence of retinal holes and IL-1beta may lead to activation of HGF, mitogen activated protein kinases (MAPK), c-jun and extracellular matrix remodeling, resulting in proliferative and migratory cells in the wounded retina.