Journal of Occupational and Environmental Medicine · 2016 · 17 citations · 21 references
Public HealthEnvironmental SciencesObstetricsAir PollutionEnvironmental HealthEpidemiologyAir PollutantsAir Pollution EpidemiologyAir QualityEnvironmental EpidemiologyExposure AssessmentParticulate MatterAir Pollution Exposure RiskAir Pollution RiskBinary Logistic RegressionCohort Study InvestigationConfidence Intervals For Odds RatiosEnvironmental Exposures During PregnancyEnvironmental Prenatal ExposuresPrenatal Air Pollution Exposure
OBJECTIVE: This study aimed to explore evidence for the influence of air pollution on the risk of birth defects in China and contribute to establish prevention strategies. METHODS: We conducted a retrospective cohort study in Anqing city, Eastern China, from 2010 to 2012. Binary logistic regression models were used to estimate odds ratios (ORs) per 10 μg/m3 change for SO2, NO2, and PM10. RESULTS: For continuous exposure to SO2 (10 μg/m increase), the adjusted OR for birth defects is 1.20 [95% confidence interval (95% CI) 1.09 to 1.29] in the preconception. A 10 μg/m increase in SO2 (adjusted OR 1.26, 95% CI 1.15 to 1.36) during the second trimester is strongly associated with birth defects. No associations have been observed for NO2 and PM10. CONCLUSION: The results suggested that exposure to ambient SO2 during pregnancy may increase the risk of birth defects.
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Air pollution and congenital heart defects
Keren Agay‐Shay, Michael Friger, Shai Linn et al. · Environmental Research · 2013 · 138 citations