Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With <i>ERBB</i> Alterations - Concepedia

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Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With <i>ERBB</i> Alterations

DOI Full Paper Access

164

Citations

43

References

2016

Year

Noura J. Choudhury, Alexa Campanile, Tatjana Antic, Kai Lee Yap, Carrie Fitzpatrick, James L. Wade, Theodore Karrison, Walter M. Stadler, Yusuke Nakamura, Peter H. O’Donnell

Journal of Clinical Oncology

Abstract

Afatinib demonstrated significant activity in patients with platinum-refractory UC with HER2 or ERBB3 alterations. The potential contribution of ERBB3 to afatinib sensitivity is novel. Afatinib deserves further investigation in molecularly selected UC.

References

	Year	Citations

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