Fibroblast Growth Factor 23 and Placental Growth Factor in Patients with Psoriasis and their Relation to Disease Severity.

Abstract

Increased serum FGF23 and PLGF levels and the presence of positive correlation between PLGF and PASI score probably reflects the inflammatory state and IR seen in psoriasis. Above mentioned correlations provide rationale for possible application of serum FGF23 and especially of PLGF measurements as biomarkers of disease severity, which could be useful for management of treatment efficacy.