Efficacy of Artesunate-mefloquine for Chloroquine-resistant<i>Plasmodium vivax</i>Malaria in Malaysia: An Open-label, Randomized, Controlled Trial

Abstract

High-grade CQ-resistant P. vivax is prevalent in eastern Malaysia. AS-MQ is an efficacious ACT for all malaria species. Wider CQ-efficacy surveillance is needed in vivax-endemic regions with earlier replacement with ACT when treatment failure is detected.Clinical Trials Registration NCT01708876.