Concepedia

Preparing (Multi)Fluoroarenes as Building Blocks for Synthesis: Nickel-Catalyzed Borylation of Polyfluoroarenes via C–F Bond Cleavage

Jing Zhou, Maximilian W. Kuntze‐Fechner, Rüdiger Bertermann, Ursula S. D. Paul, Johannes H. J. Berthel, Alexandra Friedrich, Zhen‐Ting Du, Todd B. Marder, Udo Radius

Journal of the American Chemical Society · 2016 · 206 citations · 33 references

DOI

Concepts

Abstract

The [Ni(IMes)2]-catalyzed transformation of fluoroarenes into arylboronic acid pinacol esters via C-F bond activation and transmetalation with bis(pinacolato)diboron (B2pin2) is reported. Various partially fluorinated arenes with different degrees of fluorination were converted into their corresponding boronate esters.

References

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