New England Journal of Medicine · 1966 · 21 citations · 18 references
MedicineGeneticsPediatricsCytogeneticsHuman GeneticsPediatric GeneticsChromosomal AbnormalitiesCongenital AnomaliesCongenital Disorder EpidemiologyCongenital MalformationsCongenital Skin DisordersPediatric DermatopathologyCongenital Anomalies GeneticsCongenital Skin AnomaliesDistortionsEtiology Of Congenital Anomalies
UNUSUAL and unexpected distortions of dermal patterns were first observed in chromosome aberrations.12 These reports stimulated our interest to look for other correlations. In our random screening of abnormal infants we soon became impressed with the high incidence of unusual dermatoglyphies in children with all types of major congenital malformations. Four findings appeared to occur with increased frequency in abnormal infants: simian lines; bilateral distal axial triradii; radial loops on other than the second digit; and a single flexion crease on a digit. These unusual findings occur in normal persons but are relatively rare in the general population.'3 A dermatoglyphic . . .
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MULTIPLE CONGENITAL ANOMALY CAUSED BY AN EXTRA AUTOSOME
Klaus Pätau, DavidW. Smith, Eeva Therman et al. · The Lancet · 1960 · 686 citations
David W. Smith, Klaus Pätau, Eeva Therman et al. · The Journal of Pediatrics · 1963 · 136 citations