Concepedia

GSTM, GSTT and p53 polymorphisms as modifiers of clinical outcome in colorectal cancer.

András Csejtei, Antal Tibold, Zsuzsa Varga, Katalin Koltai, Ágoston Ember, Zsuzsa Orsós, Gergely Fehér, Örs Péter Horváth, István Ember, István Kiss

PubMed · 2008 · 43 citations · 17 references

Abstract

The significance of the investigated polymorphisms in prognosis is dependent on the tumor stage. These parameters might be used in certain cases as prognostic biomarkers in clinical diagnostics and in the planning of individual therapy.

References

17

The classification of cancer of the rectum

Cuthbert Dukes · The Journal of Pathology and Bacteriology · 1932 · 1.5K citations

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Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.

Bengt Mannervik, Per Ålin, Claes Guthenberg et al. · Proceedings of the National Academy of Sciences · 1985 · 1.1K citations · Full text

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A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer

Christoph Sachse · Carcinogenesis · 2002 · 284 citations · Full text

Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13.

William R. Pearson, William R. Vorachek, S.J. Xu et al. · PubMed · 1993 · 226 citations

The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer.

B Ketterer, Jonathan M. Harris, G Talaska et al. · Environmental Health Perspectives · 1992 · 213 citations · Full text

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