Phenotypically non‐suppressive cells predominate among FoxP3‐positive cells in oral lichen planus

Abstract

The absence of actively suppressing FoxP3⁺ CD4⁺ T cells may in part explain why OLP is a remarkably persisting condition, in spite of the presence of substantially high numbers of FoxP3⁺ CD4⁺ T cells. The findings emphasize that it is crucial to examine not only numbers but also functional phenotype of FoxP3⁺ CD4⁺ T cells in human tissues.