Concepedia

Seroconversion to Antibodies against Kaposi's Sarcoma–Associated Herpesvirus–Related Latent Nuclear Antigens before the Development of Kaposi's Sarcoma

Shou‐Jiang Gao, Lawrence Kingsley, Donald R. Hoover, Thomas J. Spira, Charles R. Rinaldo, Alfred J. Saah, John Phair, Roger Detels, Preston Parry, Yuan Chang,

New England Journal of Medicine · 1996 · 604 citations · 33 references

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Abstract

In most patients with kaposi's sarcoma and AIDS, seroconversion to positivity for antibodies against KSHV-related nuclear antigens occurs before the clinical appearance of Kaposi's sarcoma. This supports the hypothesis that Kaposi's sarcoma results from infection with KSHV.

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