Concepedia

Pools of programmed death‐ligand within the oral cavity tumor microenvironment: Variable alteration by targeted therapies

Sujay Shah, Andria M. Caruso, Harrison Cash, Carter Van Waes, Clint Allen

Head & Neck · 2016 · 29 citations · 27 references

DOIFull text

Open access

Abstract

PD-L1 expressed on cancer and infiltrating immune cells is variably altered by targeted therapies and may, in part, reflect changes in tumor IFN. © 2016 Wiley Periodicals, Inc. Head Neck 38:1176-1186, 2016.

References

27

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

Suzanne L. Topalian, F. Stephen Hodi, Julie R. Brahmer et al. · New England Journal of Medicine · 2012 · 12.5K citations · Full text

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

Julie R. Brahmer, Scott S. Tykodi, Laura Q.M. Chow et al. · New England Journal of Medicine · 2012 · 7.9K citations · Full text

PD-1 blockade induces responses by inhibiting adaptive immune resistance

Paul C. Tumeh, Christina L. Harview, Jennifer H. Yearley et al. · Nature · 2014 · 6.5K citations · Full text

, , +6

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

Roy S. Herbst, Jean‐Charles Soria, Marcin Kowanetz et al. · Nature · 2014 · 5.2K citations

, , +10

Comprehensive genomic characterization of head and neck squamous cell carcinomas

Nature · 2015 · 4K citations · Full text