Concepedia

Profibrotic role of WNT10A via TGF-β signaling in idiopathic pulmonary fibrosis

Keishi Oda, Kazuhiro Yatera, Hiroto Izumi, Hiroshi Ishimoto, Sohsuke Yamada, Hiroyuki Nakao, Tetsuya Hanaka, Takaaki Ogoshi, Shingo Noguchi, Hiroshi Mukae

Respiratory Research · 2016 · 54 citations · 37 references

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Abstract

WNT10A plays an important role in the pathogenesis of IPF via TGF-β activation and it may also be a sensitive predictor for the onset of an AE-IPF.

References

37

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Ganesh Raghu, Harold R. Collard, Jim Egan et al. · American Journal of Respiratory and Critical Care Medicine · 2011 · 7.1K citations · Full text

Simple method of estimating severity of pulmonary fibrosis on a numerical scale.

T Ashcroft, Judy M. Simpson, V. Timbrell · Journal of Clinical Pathology · 1988 · 1.7K citations · Full text

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Alveolar epithelial cell mesenchymal transition develops <i>in vivo</i> during pulmonary fibrosis and is regulated by the extracellular matrix

Kevin K. Kim, Matthias C. Kugler, Paul J. Wolters et al. · Proceedings of the National Academy of Sciences · 2006 · 1.2K citations · Full text

, , +19

Double-blind, Placebo-controlled Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

Arata Azuma, Toshihiro Nukiwa, Eiyasu Tsuboi et al. · American Journal of Respiratory and Critical Care Medicine · 2005 · 944 citations

, , +16

Adult-onset pulmonary fibrosis caused by mutations in telomerase

Kalliopi Tsakiri, Jennifer T. Cronkhite, Phillip J. Kuan et al. · Proceedings of the National Academy of Sciences · 2007 · 873 citations · Full text