HIV virological failure and drug resistance in a cohort of Tanzanian HIV-infected adults

Abstract

High levels of early ART failure and drug resistance were observed among Tanzanian HIV-1-infected adults enrolled in a well-monitored study. Initiating treatment early and ensuring optimal adherence are vital for the success and durability of first-line ART in these settings.

References

Page 1

	Year	Citations
Efficacy and Safety of Tenofovir DF vs Stavudine in Combination Therapy in Antiretroviral-Naive Patients<SUBTITLE>A 3-Year Randomized Trial</SUBTITLE> Joel E. Gallant JAMA	2004	1.3K
Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study Linda Wittkop, Huldrych F. Günthard, Frank de Wolf, The Lancet Infectious Diseases Transmitted Drug ResistanceTreatment And PreventionHuman RetrovirusAntiviral TherapyEuropean Multicohort Study	2011	381
Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis Ravindra K. Gupta, Michael R. Jordan, Binta Sultan, The Lancet Sexual HealthPreventive MedicineTreatment And PreventionMedicineGlobal Health	2012	360
The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy Mina C. Hosseinipour, Joep JG van Oosterhout, Ralf Weigel, AIDS	2009	284
Prevalence of HIV‐1 Drug Resistance after Failure of a First Highly Active Antiretroviral Therapy Regimen in KwaZulu Natal, South Africa Vincent C. Marconi, Henry Sunpath, Zhigang Lu, Clinical Infectious Diseases	2008	236
Predictors of Incomplete Adherence, Virologic Failure, and Antiviral Drug Resistance among HIV-Infected Adults Receiving Antiretroviral Therapy in Tanzania Habib O. Ramadhani, Nathan M. Thielman, Keren Z. Landman, Clinical Infectious Diseases	2007	196
Effect of pretreatment HIV-1 drug resistance on immunological, virological, and drug-resistance outcomes of first-line antiretroviral treatment in sub-Saharan Africa: a multicentre cohort study Raph L Hamers, Rob Schuurman, Kim Sigaloff, The Lancet Infectious Diseases Drug-resistance OutcomesHiv/aids CounsellingTreatment And PreventionHuman RetrovirusGlobal Health	2011	194
Unnecessary Antiretroviral Treatment Switches and Accumulation of HIV Resistance Mutations; Two Arguments for Viral Load Monitoring in Africa Kim Sigaloff, Raph L Hamers, Carole L. Wallis, JAIDS Journal of Acquired Immune Deficiency Syndromes	2011	184
Patterns of HIV-1 Drug Resistance After First-Line Antiretroviral Therapy (ART) Failure in 6 Sub-Saharan African Countries: Implications for Second-Line ART Strategies Raph L Hamers, Kim Sigaloff, Annemarie M. J. Wensing, Clinical Infectious Diseases	2012	160
Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa DART Virology Group and Trial Team AIDS	2006	130

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