Concepedia

Molecular subtype approximated by quantitative estrogen receptor, progesterone receptor and Her2 can predict the prognosis of breast cancer.

Xiao Song Chen, Chuan Dong, Jia Wu, Wen Tao Yang, Hong Lu, Jiong Wu, Jin Lu, Zhi Min Shao, Zhen Shen, Kun Wei Shen

PubMed · 2010 · 37 citations · 23 references

DOI

Abstract

Breast cancer subtypes based on quantitative ER, PR, and Her2 may be predictive of prognosis. Patients whose tumors were not HR+/Her2- had a worse outcome in our study.

References

23

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Charles M. Perou, Thérese Sørlie, Michael B. Eisen et al. · Nature · 2000 · 16.1K citations

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Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.6K citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Thérese Sørlie, Charles M. Perou, Robert Tibshirani et al. · Proceedings of the National Academy of Sciences · 2001 · 10.8K citations · Full text

Cancer Statistics, 2007

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2007 · 7.5K citations · Full text

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Studies of the HER-2/ <i>neu</i> Proto-Oncogene in Human Breast and Ovarian Cancer

Dennis J. Slamon, William Godolphin, Lovell A. Jones et al. · Science · 1989 · 6.8K citations