Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson’s Disease

Abstract

Our data suggest that the impact of additional untested coding variants in the GBA and LRRK2 genes is higher than previously estimated. Our data also provide compelling evidence of the existence of additional untested variants in the primary Mendelian and PD GWAS genes that contribute to the genetic etiology of sporadic PD.