Hepatitis and Cirrhosis in Women with Positive Clot Tests for Lupus Erythematosus

Abstract

ONLY insignificant histologic changes are ordinarily described in the liver of patients with lupus erythematosus, and the occurrence of jaundice is so rare that it is usually considered an incidental finding. Lupus erythematosus has rarely been regarded as a potential etiologic factor in the small group of patients presenting the problem of prolonged jaundice. The purpose of this study is to describe a group of women (mostly young adults) who presented not only prolonged jaundice with evidence of grave impairment of the liver but also hypergammaglobulinemia, the lupus-erythematosus-cell (L.E.-cell) phenomenon and clinical evidence of diffuse lupus erythematosus. Beam and his . . .