Inhibition of bone loss with surface-modulated, drug-loaded nanoparticles in an intraosseous model of prostate cancer

Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy <i>in vivo</i>

Omid C. Farokhzad, Jianjun Cheng, Benjamin A. Teply et al. · Proceedings of the National Academy of Sciences · 2006 · 1.6K citations · Full text

Pharmacy, Oncology, Pharmaceutics +17

Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel.

Neil Desai, Vuong Trieu, Zhiwen Yao et al. · Clinical Cancer Research · 2006 · 1.2K citations

Medicine, Oncology, Pharmacology +14

Noninvasive Imaging of Quantum Dots in Mice

Byron Ballou, B. Christoffer Lagerholm, Lauren A. Ernst et al. · Bioconjugate Chemistry · 2003 · 1.1K citations

Natural Sciences, Biomedical Engineering, Materials Science +17

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

Jeffrey S. Hrkach, Daniel D. Von Hoff, Mir Mukkaram Ali et al. · Science Translational Medicine · 2012 · 1.1K citations

Pharmacy, Pharmaceutics, Pharmacology +17

Rapid endo‐lysosomal escape of poly(DL‐lactide‐ <i>co</i> glycolide) nanoparticles: implications for drug and gene delivery

Jayanth Panyam, Wenzhong Zhou, Swayam Prabha et al. · The FASEB Journal · 2002 · 1K citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17