The macrophage activation marker <scp>sCD</scp>163 is associated with morphological disease stages in patients with non‐alcoholic fatty liver disease

Abstract

Soluble CD163 reflecting macrophage activation is associated with morphological features of NAFLD suggesting their involvement in the pathogenesis of NAFLD, NASH and particularly fibrosis. An independent association between sCD163 and cytokeratin-18 suggests that apoptosis may contribute to macrophage activation in NAFLD/NASH.