PubMed · 1993 · 18 citations · 0 references
MedicineInfectious DiseasesInternal MedicineDiabetologyGastroenterologyMedical MicrobiologyDiabetes MellitusGastric DiseasesGastric DisordersGastrointestinal PathologyPeptic Ulcer DiseaseControl Group DesignGastric PathologyGastric Ulcer DiseaseHelicobacter Pylori InfectionHelicobacter Pylori PathogenesisHelicobacter Pylori TestingMatched Control Group
The authors assessed the frequency of Helicobacter pylori in diabetic patients with gastroduodenal ulceration and non-ulcerative dyspepsia. They evaluated a group of 91 hospitalized type II diabetics which non-ulcerative dyspepsia, endoscopically confirmed ulceration of the duodenal bulbus and gastric ulceration. The control group was formed by 98 hospitalized non-diabetic subjects. Between the two groups there was no difference in the frequency of Helicobacter pylori in non-ulcerative dyspepsia (61.1% as compared with 56.0% in non-diabetics) and gastric ulceration (75.0% as compared with 77.7% in non-diabetics). There is a significantly (p > 0.005) lower incidence of HP infection in diabetics with active duodenal ulceration (46.6%), as compared with non-diabetics (87.5%). The authors assume that active duodenal ulceration in diabetics could be more frequently caused by other factors than Helicobacter pylori.