Journal of Bone and Joint Surgery - British Volume · 2005 · 156 citations · 10 references
Retrospective StudyBone DiseaseIntralesional CurettageAggressive BehaviourMedicineSurgical PathologyBone RepairOsteoarthritisSurgeryJoint ReplacementChondrogenesisOncologySpinal OncologyOsteoporosisOrthopaedic Surgery
We undertook this retrospective study to determine the rate of recurrence and functional outcome after intralesional curettage for chondroblastoma of bone. The factors associated with aggressive behaviour of the tumour were also analysed. We reviewed 53 patients with histologically-proven chondroblastoma who were treated by intralesional curettage in our unit between 1974 and 2000. They were followed up for at least two years to a maximum of 27 years. Seven (13.2%) had a histologically-proven local recurrence. Three underwent a second intralesional curettage and had no further recurrence. Two had endoprosthetic replacement of the proximal humerus and two underwent below-knee amputation after aggressive local recurrence. One patient had the rare malignant metastatic chondroblastoma and eventually died. The mean Musculoskeletal Tumour Society functional score of the survivors was 94.2%. We conclude that meticulous intralesional curettage alone can achieve low rates of local recurrence and excellent long-term function.
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Arun J. Ramappa, FRANCIS Y. I. LEE, Peter Tang et al. · Journal of Bone and Joint Surgery · 2000 · 237 citations