Biomedical Research-tokyo · 2005 · 13 citations · 0 references
Life SciencesPlant SciencesToxicologyPharmaceutical ToxicologyPlant BiochemistryToxicologic PathologyMechanisms Of Toxic InjuryMedicinal PlantsPoisonous PlantsRodent ToxicologyToxic PlantsGastrointestinal Plant ToxicityHerbal Remedy ToxicityHerbal ToxicityPhytochemical CompositionToxic Mushroom CompoundsToxicity Of Alkaloid-containing PlantsToxicity Of Medicinal PlantsToxicology Of Medicinal Plants
The aqueous leaf extract, after six weeks administration showed a decrease in weight of the treated animals, whereas body weight of the un-treated animals rose progressively as the period increased. Phytochemical screening of the plant reveals the presence of saponins, alkaloids and volatile oils. Pathological features like congestion of the lungs, metaplastic changes in the mucosal surface of the stomach, and necrosis of the kidney tubules were noticed. These abnormalities may possibly not develop with C. ambrosioides used for a short period.