In vitro studies on the anticancer activity of Bacopa monnieri

Abstract

B. monnieri plant extract has been reported to have anticancer property. Different concentrations of ethanolic extract of B. monnieri were tested with Sarcoma-180 cell culture. The cell growth, viability and 3 H-thymidine incorporation into the DNA were assessed. Sarcoma-180 cell growth was significantly inhibited with increasing concentrations of B. monnieri. 3 H-thymidine uptake study suggested that the site of action of the drug may be at DNA replication stage. Hence, the alcoholic extract of B. monnieri can be considered as an anticancer drug.