The Mechanism of Hypoproteinemia Associated with Giant Hypertrophy of the Gastric Mucosa

Abstract

GIANT hypertrophy of the gastric mucosa has been known under many synonyms, which include Menetrier's disease, polyadénome en nappe, polyadénome polypeux, giant hypertrophic gastritis, tumor-simulating gastritis and giant hypertrophy of the gastric rugae. It is a relatively uncommon lesion of the stomach. Hypoproteinemia has been described in some cases of this disease. In the present report, the mechanism of hypoproteinemia in a patient was investigated with I131-labeled albumin. This patient was subsequently examined at autopsy.Review of the LiteratureThe clinical aspects of giant hypertrophy of the gastric mucosa are described in several recent studies.1 2 3 4 In reviewing 47 cases . . .