The role of Rebamipide ophthalmic suspension in management of dry eye disease

Abstract

Purpose of review: Review of the drug Rebamipide, an ophthalmic suspension, in the treatment of dry eye and other ocular surface disorders. Method: An extensive literature search was done on articles published in various ophthalmic journals to review the work on the latest drug rebamipide and its role in treating dry eye and other ocular surface disorders. Recent Findings: Rebamipide is a novel drug for the treatment of dry eye disorders. It is a mucin-secretogogue, has a cytoprotective, anti-inflammatory effect and also suppresses the detrimental oxygen free radicals and helps in faster healing of epithelium. No major side effect has been noticed apart from dysguesia. Summary: Rebamipide is the latest drug introduced in the treatment of dry eye. It seems to be a safe and effective treatment in   chronic and severe forms of dry eye particularly due to mucus deficiency. Key Words: Dry eye, Goblet cell, Microvilli, Rebamipide, Tear film