Transient High Levels of Viremia in Patients with Primary Human Immunodeficiency Virus Type 1 Infection
New England Journal of Medicine · 1991 · 843 citations · 16 references
Although p24 core antigenemia and viral isolation have previously been described during primary HIV-1 infection, this report documents the large viral burden during the acute phase of infection. The rapid and spontaneous decline in the viral load suggests an effective immune response in the host that, if understood, may be used to combat AIDS.
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Jerome A. Zack, Salvatore J. Arrigo, Stacy Weitsman et al. · Cell · 1990
Quiescent Primary LymphocytesViral ReplicationHuman Retrovirus+11
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