Transient High Levels of Viremia in Patients with Primary Human Immunodeficiency Virus Type 1 Infection

Abstract

Although p24 core antigenemia and viral isolation have previously been described during primary HIV-1 infection, this report documents the large viral burden during the acute phase of infection. The rapid and spontaneous decline in the viral load suggests an effective immune response in the host that, if understood, may be used to combat AIDS.