Current Organic Chemistry · 2013 · 47 citations · 0 references
Natural SciencesCell BiologyChemical BiologyCell BiophysicsMolecular Cell BiologyMolecular ImagingCellular ImagingChemical Probe DiscoveryFluorescence ImagingFluorescence MicroscopyFluorescence SpectroscopyMolecular Probe DevelopmentFluorescence ProbesFluorescent LabelingFluorescent ProbesFluorophore ChemistryFluorophore DesignLive-cell Fluorescence ImagingLive-cell Imaging ProbesMolecular Imaging Probes
In this review, major categories of molecular fluorophores were summarized with emphasis on their synthetic strategies and chemical transformations. Recent advancement in small-molecule fluorophores as novel molecular probes in living cells was also discussed. Keywords: Fluorophore, Synthesis, Fluorescent imaging, Molecular probe, Cellular molecules, Live cells