Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.6K citations

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

Morten Hansen, Svend Erik Nielsen, Kurt Berg · Journal of Immunological Methods · 1989 · 3.5K citations

Cell Growth/cell, Immunocytochemical Technique, Rapid Dye Method +7

Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease

Melody Cobleigh, Charles L. Vogel, Debu Tripathy et al. · Journal of Clinical Oncology · 1999 · 2.8K citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

A Ullrich, Lisa M. Coussens, Joel S. Hayflick et al. · Nature · 1984 · 2.8K citations

Tumor Biology, Carcinoma Cells, Medicine +9

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

Diana Graus-Porta · The EMBO Journal · 1997 · 1.6K citations · Full text

Signal Transduction, Molecular Physiology, Synaptic Signaling +11