Variations in Susceptibility of Three Selected Strains of Chickens to Cell Suspensions of JM Virus

Abstract

Experiments to determine the feasibility of breeding strains of chickens that are resistant to leukosis have been conducted for many years by natural exposure (Hutt and Cole, 1957). Though progress was made over many years of time, such exposure was unpredictable and unmeasurable. In 1962, it was shown that the artificial inducement of leucosis with known doses of JM virus was repeatable at given levels with respective strains or families of chickens, some at one hundred percent levels, or nearly so, (Sevoian et al., 1962). At that time this technique was used to evaluate many strains and sources of fowl among which were S-, C-, and K-lines of White Leghorn chickens developed for susceptibility (S) and resistance (C and K) to natural exposures of leukosis over a period of about 25 years by Drs. F. B. Hutt and R. K. Cole of Cornell University. Using leukotic tumor cells suspended in . . .