Vibration Measurements on Dissolution Systems and Effects on Dissolution of Prednisone Tablets RS

Abstract

Efforts are being made by various groups (1,2) to focus more on mechanical calibration as a potential replacement for Prednisone tablets RS (calibrator tablets). Although some mechanical calibration is currently performed (e.g.,wobble,centering), the PhRMA committee's original proposal was to replace the Prednisone tablets RS through use of enhanced mechanical calibration.