Studies on O-alkylated imides. II. Some reactions of O-ethyl succinimide and O-ethyl 4,4-dimethyl-glutarimide.

Abstract

O-Ethyl succinimide (I) and O-ethyl 4, 4-dimethylglutarimide (II) were reacted with active methylene compounds (ethyl cyanoacetate and ethyl acetoacetate), phenylhydrazine and its derivatives, and N-bromosuccinimide. Furthermore, the salt formation of the cyanoacetylidene compound (III), the hydrolysis of the acetoacetylidene compound (VIII), the Fischer indolization of the imidrazones (XIII and XIV), and the Favorskii rearrangement of the 3-bromo-imides (XX and XXI) were examined.