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The Influence of Glucocorticoids on Plasma Cholinesterase
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1974
Year
Plasma CholinesterasePlasma ButyrylcholinesterasePharmacotherapyGlucocorticoidCellular PhysiologyAdrenal GlandPharmacological StudyDaily Subcutaneous InjectionNeurochemistryAnimal PhysiologyBuche ActivityNervous SystemEndocrinologyPharmacologyPhysiologyVeterinary ScienceAnesthesiaMedicineAnesthesiology
The daily subcutaneous injection of 10 mg/kg methyl-prednisolone or 2 mg/kg dexamethasone for 12 days to mongrel dogs caused a significant decrease of plasma butyrylcholinesterase (BuChE) activity. BuChE activity returned toward pre-drug values after discontinuation of gluco-corticoids. There were no changes in erythrocyte AChE activity.