Concepedia

Palladium-Catalyzed Synthesis of 2,3,4-Trisubstituted Furans via Cascade Reactions of Aryloxy-enynes with Aryl Halides

Ende Li, Xingcan Cheng, Chengyu Wang, Yushang Shao, Yanzhong Li

The Journal of Organic Chemistry · 2012 · 29 citations · 36 references

DOI

Concepts

Abstract

A highly efficient palladium-catalyzed cascade reactions of aryloxy-enynes with aryl halides under mild reaction conditions has been developed. This methodology offers rapid access to 2,3,4-trisubstituted furans in good to excellent yields in a regioselective manner.

References

36

AuCl<sub>3</sub>-Catalyzed Synthesis of Highly Substituted Furans from 2-(1-Alkynyl)-2-alken-1-ones

Tuanli Yao, Xiaoxia Zhang, Richard C. Larock · Journal of the American Chemical Society · 2004 · 487 citations

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Homogeneous Gold-Catalyzed Oxidative Carboheterofunctionalization of Alkenes

Guozhu Zhang, Li Cui, Yanzhao Wang et al. · Journal of the American Chemical Society · 2010 · 439 citations

, , +16

Syntheses of polysubstituted furans: recent developments

Stefan F. Kirsch · Organic & Biomolecular Chemistry · 2006 · 371 citations

, , +13

Mechanistically Diverse Copper-, Silver-, and Gold-Catalyzed Acyloxy and Phosphatyloxy Migrations:  Efficient Synthesis of Heterocycles via Cascade Migration/Cycloisomerization Approach

Todd Schwier, Anna W. Sromek, Dahrika M. L. Yap et al. · Journal of the American Chemical Society · 2007 · 296 citations · Full text

, , +15

Gold(III) Porphyrin-Catalyzed Cycloisomerization of Allenones

Cong‐Ying Zhou, Philip Wai Hong Chan, Chi‐Ming Che · Organic Letters · 2005 · 290 citations

, , +11