The Evaluation of p16ink4a Immunoexpression/Immunostaining and Human Papillomavirus DNA Test in Cervical Liquid-Based Cytological Samples

Human papillomavirus is a necessary cause of invasive cervical cancer worldwide

Jan M.M. Walboomers, Marcel V. Jacobs, M. Michele Manos et al. · The Journal of Pathology · 1999 · 9K citations

Overexpression of p16INK4A as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri

Ruediger Klaes, Tibor Friedrich, Dimitry Spitkovsky et al. · International Journal of Cancer · 2001 · 1K citations · Full text

Neoplastic Epithelial Cells, Pathology, Gynecology +22

Ki-67, Cyclin E, and p16 INK4 Are Complimentary Surrogate Biomarkers for Human Papilloma Virus-Related Cervical Neoplasia

Jeffrey T. Keating, Aida Čviko, Sabine Riethdorf et al. · The American Journal of Surgical Pathology · 2001 · 436 citations

Immunology, Gynecology, Pathology +17

The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability.

Stefan Duensing, Karl Münger · PubMed · 2002 · 395 citations

Cytogenetics, Pathology, Molecular Biology +16

p16INK4a Expression Correlates with Degree of Cervical Neoplasia: A Comparison with Ki-67 Expression and Detection of High-Risk HPV Types

S. Nicholas Agoff, Patricia Lin, Janice Morihara et al. · Modern Pathology · 2003 · 253 citations · Full text

Cervical Cancer Screening, Cervical Cancer, Medicine +10