Fungal Metabolites. XV. Primary Structures of Antibiotic Peptides, Hypelcins B-I, B-II, B-III, B-IV and B-V, from Hypocrea peltata. Application of Electrospray Mass Spectrometry and Electrospray Mass Spectrometry/Mass Spectrometry.

Abstract

Hypelcin B is a mixture of antibiotic peptides produced by Hypocrea peltata. Hypelcins B-I, B-II, B-III, B-IV and B-V are components of this mixture purified by reversed-phase high-performance liquid chromatography. The amino acid sequences of these peptides were determined by electrospray mass spectrometry and electrospray mass spectrometry/mass spectrometry. The molecular weights of these peptides were all ca. 2000 and the structures were very similar.