Concepedia

Family History, Surgery, and APC Mutation Are Risk Factors for Desmoid Tumors in Familial Adenomatous Polyposis: An International Cohort Study

Marry H. Nieuwenhuis, Jérémie H. Lefèvre, Steffen Bülow, Heikki Järvinen, Lucio Bertario, Solen Kernéis, Yann Parc, Hans F. A. Vasen

Diseases of the Colon & Rectum · 2011 · 142 citations · 10 references

DOI

Abstract

A positive family history for desmoid tumors, abdominal surgery, and APC mutation site are significant risk factors for development of desmoid tumors. The results may have implications for determining the optimal management of FAP patients and guide future studies.

References

10

Guidelines for the clinical management of familial adenomatous polyposis (FAP)

Hans F. A. Vasen, Gabriela Möslein, Ángel Alonso et al. · Gut · 2008 · 691 citations · Full text

, , +7

Familial adenomatous polyposis: desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444

Reiner Caspari, S Olschwang, Waltraut Friedl et al. · Human Molecular Genetics · 1995 · 367 citations

Desmoid tumours in familial adenomatous polyposis.

Ahmet Kemal Gürbüz, Francis M. Giardiello, Gloria M. Petersen et al. · Gut · 1994 · 353 citations · Full text

, , +16

Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis

Lucio Bertario, Antonio Russo, Paola Sala et al. · International Journal of Cancer · 2001 · 225 citations

, , +20

A nation‐wide study comparing sporadic and familial adenomatous polyposis‐related desmoid‐type fibromatoses

Marry H. Nieuwenhuis, M. K. Casparie, Lisbeth Mathus-Vliegen et al. · International Journal of Cancer · 2010 · 216 citations · Full text