The Effects of Tianeptine, Olanzapine and Fluoxetine on the Cognitive Behaviors of Unpredictable Chronic Mild Stress-exposed Mice

Abstract

Quantitative real-time PCR revealed that CREB and BDNF gene expression levels were significantly decreased in UCMS-exposed group, and this effect was significantly reversed by each of drugs tested. Our results seem to be test dependent and should be further investigated using different learning and memory tasks.