Australian Journal of Chemistry · 1979 · 76 citations · 0 references
Life SciencesBiochemistryBotanyCoral Reef BiologyCoral Reef EcologyMarine EcologyMarine Bioactive CompoundsMarine Natural Product BiosynthesisMarine Natural ProductsReef-building CoralsTerpenoid BiosynthesisAbsolute Configuration AssignmentAbsolute Configuration DeterminationBioactive Compounds From Marine SpongesCircular DichroismCircular Dichroism AnalysisMarine Sponge MetabolitesSingle Crystal AnalysisSponges-derived Metabolites
Great Barrier Reef sponges of the genus Spongia have yielded eight closely related tetracyclic furanoditerpenes. The structures, assigned on the basis of spectral methods, have been confirmed by a single-crystal X-ray analysis of one of the metabolites and the relative stereochemical features have been defined. The absolute configuration of this metabolite was determined by circular dichroism, which allowed the relationship between the eight new compounds to be determined.