Degradation of target coverage due to inter-fraction motion during intensity-modulated proton therapy of prostate and elective targets

Abstract

The most severe dose degradations were found for CTV-sv, but they were also evident for CTV-ln. The degradations could not be completely resolved, neither by using the largest margin expansion nor with the choice of set-up. With fiducial set-up CTV-p was robust against the inter-fraction changes.