Histopathological changes in liver, kidney and muscles of pesticides exposed malnourished and diabetic rats.

Nidhi Benjamin, Ameeta Kushwah, Rajiv Sharma, A. K. Katiyar

PubMed · 2006 · 40 citations · 4 references

Concepts

Abstract

Histopathological changes were observed in liver, kidney and muscles of normal, protein-malnourished, diabetic as well as both protein-malnourished and diabetic albino rats when exposed to a mixture of monocrotophos, hexachlorocyclohexane and endosulfan at varying intervals. The examination revealed hepatotoxic, nephrotoxic and muscular necrotic effects in pesticides exposed rats. Toxicity was aggravated in protein-malnourished and diabetic animals and more so, if the animals were both diabetic and protein-malnourished.

References

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