Synthesis of 3‐Arylpyridines <i>via</i> Palladium/Copper‐Catalyzed Annulation of Allylamine/1,3‐Propanediamine and Aldehydes

Abstract

Abstract A novel and efficient method for the synthesis of 3‐arylpyridines from allylamine/propanediamine and aldehydes by palladium/copper‐catalyzed oxidative tandem cyclization has been developed. With this reaction, a series of desired 3‐arylpyridines was synthesized in moderate yields via CC/CN bond formation and 6‐ endo/exo‐trig cyclization. magnified image