A comparison of the efficacy and tolerance of an aqueous beclomethasone dipropionate nasal spray with the conventional pressurized spray

Abstract

Forty-two subjects took part in a double-blind, double-dummy, parallel group study to compare the efficacy and tolerance of a nasal spray containing an aqueous suspension of beclomethasone dipropionate with the conventional pressurized spray in controlling the symptoms of seasonal rhinitis. Each patient received 100 micrograms beclomethasone dipropionate into each nostril twice daily for 14 days. Evaluation of daily symptom scores, and the physician's and subjects' assessment of treatment, demonstrated that both sprays were equally effective in alleviating symptoms and with a similar low incidence of side-effects. The aqueous spray may be considered an effective alternative treatment in the management of seasonal rhinitis.