Apparent Molal Volumes and Viscosity <i>B</i>-Coefficients of Acetyl Salicylic Acid (2-Acetoxy Benzoic Acid) Solutions in Higher Alcohols at Different Temperatures

Abstract

Aspirin is used as an analgesic, antipyretic, and anti-inflammatory drug. Density and viscosity of acetyl salicylic acid (2-acetoxy benzoic acid) in propan-1-ol, propan-2-ol, butan-1-ol, and butan-2-ol at temperatures in the range (293.15 to 313.15) K have been measured in a molality range of (9.5·10−3 to 31.9·10−3) mol·kg−1 with the help of a commercially available vibrating-tube densimeter and viscometer. From the density data, apparent molal volume (Vϕ), partial molal volume (Vm0), isobaric thermal expansion coefficient (α2), partial molal expansivity (E20), Hepler's constant (δ2Vm0/δT2), and transfer volume (ΔVm0) are calculated. The viscosity data are analyzed by the Jones−Dole equation to determine the values of the viscosity B-coefficient.