Regulation of Alkaline Phosphatase in Human Cell Cultures

Abstract

The application of cell culture to human genetics requires an understanding of the relationship between a cell in culture, the tissue from which it was derived, and the genetic constitution of the donor. Differences between cells in culture derived from different tissues and organs would be useful for studies of cellular control mechanisms and differentiation. If functions characteristic of one tissue could be induced to develop in cells derived from another tissue, the chemical nature of embryological evocation and the mechanism of cell competence would be approachable.