Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm

Maximum Likelihood from Incomplete Data Via the <i>EM</i> Algorithm

A. P. Dempster, N. M. Laird, Donald B. Rubin · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1977 · 49.7K citations

Public Health, Biostatistics, Bayesian Data Analysis +16

Performing the Exact Test of Hardy-Weinberg Proportion for Multiple Alleles

Sun‐Wei Guo, Elizabeth A. Thompson · Biometrics · 1992 · 4.9K citations

Life Sciences, Biostatistics, Genetics +13

Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.

Laurent Excoffier, Montgomery Slatkin · Molecular Biology and Evolution · 1995 · 2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +9

THE EVOLUTIONARY DYNAMICS OF COMPLEX POLYMORPHISMS,,

Richard C Lewontin, Kenichi Kojima · Evolution · 1960 · 662 citations

Life Sciences, Evolutionary Biology, Genetics +10

Estimation of linkage disequilibrium in randomly mating populations

William G. Hill · Heredity · 1974 · 620 citations

Life Sciences, Biostatistics, Genetics +10