Inter‐ and Intraobserver Agreement in 24‐hour Combined Multiple Intraluminal Impedance and pH Measurement in Children

Abstract

Most measurements showed substantial to perfect intra- and interobserver agreement. Still, we found a few outliers presumably caused by poorer signal quality in some tracings rather than being observer dependent. An improvement of analysis results may be achieved by using a standard analysis protocol, a standardized method for judging tracing quality, better training options for method users, and more interaction between investigators from different institutions.