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Selective Accumulation of Cd115 by Cortex of Rat Kidney.
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1957
Year
Renal PathologyCellular PhysiologyRenal FunctionToxicologyYoung RatChronic Kidney DiseaseCell SignalingTrace ElementTrace MetalRenal PathophysiologyCell BiologyKidney CortexUrologyBioactive MetalPhysiologySelective AccumulationMetal ToxicityMedicineNephrologyKidney Research
SummaryUsing radioisotopes another element, cadmium, has been found to selectively accumulate in one tissue, the kidney cortex of the rat, in concentrations sufficient to warrant its use as a research tool. The cortex of the young rat, which contains only one-third the number of nephron units found in the adult, is unable to concentrate Cd115 at the adult level. The studies reported indicate a possible physiological role of cadmium in renal function.