Quantification and Characterization of Radiation-Induced Changes to Mandibular Vascularity Using Micro–Computed Tomography

Abstract

The results of our study specifically quantify the corrosive affects of XRT on the vasculature of the mandible. The data from this novel technique go even further and imply retention of blood vessels but a degradation of their quality and size. Further experiments can now be directed at therapeutic interventions to reverse this process and better understand the underlying mechanism of XRT-induced bone injury.