Cell-mediated drug delivery by gingival interdental papilla mesenchymal stromal cells (GinPa-MSCs) loaded with paclitaxel

A.T. Brini, Valentina Coccè, Lorena Maria Ferreira, Chiara Giannasi, Gianguido Cossellu, Aldo Bruno Giannì, Francesca Angiero, Arianna Bonomi, Luisa Pascucci, Maria Laura Falchetti,

Expert Opinion on Drug Delivery · 2016 · 49 citations · 41 references

Abstract

The procedure to obtain MSCs from interdental papilla is less invasive than that used for both bone marrow and adipose tissue, GinPa-MSCs are easy to expand and can be efficiently loaded with PTX. Taken together these qualities suggest that GinPa-MSCs may prove to be a good tool for cell-mediated drug delivery in cancer, particularly if related to stomatognathic system.

References

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