Pathologic Mechanism of Experimental Scoliosis in Pinealectomized Chickens

Masafumi Machida, Jean Dubousset, Takako Satoh, Ichiro Murai, Kirkham B. Wood, Thoru Yamada, Ryu Junnosuke

Spine · 2001 · 64 citations · 38 references

Abstract

Because there normally is evidence of lordosis in the thoracic spine of chickens, the rotational instability of the spine induced by pinealectomy may produce a scoliotic deformity as a secondary phenomenon. Pinealectomy in chickens consistently produces scoliosis with anatomic characteristics similar to those of human idiopathic scoliosis. The authors believe that disturbance of the equilibrium and the posture mechanism associated with a defect in melatonin synthesis after pinealectomy may promote the development of rotational lordoscoliosis.

References

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