Inhibitors of prostaglandin biosynthesis from Alpinia officinarum.

Abstract

Three new diarylheptanoids were isolated as inhibitors of prostaglandin biosynthesis from the methanol extract of Alpinia offioinarum Hance. Their structures were elucidated to be 7-(4 "-hydroxy-3"-methoxyphenyl)-1-phenyl-3, 5-heptadione (I), 5-methoxy-7-(4 "-hydroxy-3"-methoxyphenyl)-1-phenyl-3-heptanone (IV), and 5-hydroxy-7-(4"-hydroxyphenyl)-1-phenyl-3-heptanone (VI) by the interpretation of spectral data.